Evasionofhostimmuneresponses is well documented for viruses and may also occur during tumor immunosurveillance.
1
Tumor immuneescape has been a major problem for developing effective immunotherapy.
2
Augmenting immune surveillance and suppressing immuneescape are crucial in tumor immunotherapy.
3
Recent evidence has revealed that oncogenic mutations may confer immuneescape.
4
The HPV protein responsible for inducing this immuneescape has not been determined.
5
Secondly, graft failure and the immuneescape of extramedullary plasmocytoma have been reported.
1
This finding led us to hypothesize that a conserved structural basis of antigenicescape from anti-AMA-1 exists.
2
Here, we describe the evolution of antigenicescape variants in a rhesus macaque that developed unusually high neutralizing antibody titers to SIVmac239.
3
By using an in vitro model of antigenicescape, the inhibitory contribution of 24 polymorphic sites of the 3D7 AMA-1 vaccine was determined.
Uso de immune evasion em inglês
1
This is particularly true for HIV, which has developed numerous immuneevasion mechanisms.
2
For example, tumor cells have been shown to develop active immuneevasion mechanisms.
3
Therefore, viruses have developed mechanisms to target TRIMs for immuneevasion.
4
Exhaustion and suppression of antiviral immune responses can result in viral immuneevasion.
5
This immuneevasion mechanism imposes limitations on antibody-based vaccination and convalescent serum therapy.
6
In this regard, hypoxia orchestrates both angiogenesis and immuneevasion to support tumor growth.
7
Several mechanisms of filoviral innate immuneevasion have been defined and are reviewed here.
8
This revealed atomic details of gp120-receptor interactions and suggested multiple mechanisms of immuneevasion.
9
Tregs are important mediators of active immuneevasion in cancer.
10
Our results suggest persistence of C. glabrata within macrophages as a possible immuneevasion strategy.
11
Research is suggested into possible immuneevasion mechanisms, including the secretion of an inhibitory molecule.
12
Background: Mouse studies show that tumor-derived prostaglandins and platelets promote melanoma progression and immuneevasion.
13
This is the first report describing an immuneevasion mechanism utilized by B. spielmanii sp.
14
This is compounded by mechanisms of immuneevasion and immunosuppression that develop in the tumour microenvironment.
15
There are many identified mechanisms of this immuneevasion that can be measured both phenotypically and functionally.
16
A greater understanding of these innate immuneevasion mechanisms may suggest novel therapeutic approaches for these deadly pathogens.